|
|
ATP + HCO3- + NH3 <=> ADP + phosphate + Carbamoyl_phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
M
|
|
BRENDA:
BR137
KEGG:
R07641
MetaCyc:
RXN-13202
|
|
|
|
ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
BMK
|
|
BRENDA:
BR152
KEGG:
R00575
MetaCyc:
CARBPSYN-RXN
SABIO-RK:
203
|
|
|
|
pyruvate + HCO3- + ATP <=> H+ + oxaloacetate + ADP + phosphate
|
6.4.1.1
pyruvate carboxylase
|
–
|
BMK
|
|
BRENDA:
BR153
KEGG:
R00344
MetaCyc:
PYRUVATE-CARBOXYLASE-RXN
SABIO-RK:
105
|
|
|
|
ATP + propionyl-CoA + HCO3- <=> H+ + (S)-methylmalonyl-CoA + phosphate + ADP
|
6.4.1.2
acetyl-CoA carboxylase
6.4.1.3
propionyl-CoA carboxylase
|
–
–
|
BMK
|
|
BRENDA:
BR155
KEGG:
R01859
MetaCyc:
PROPIONYL-COA-CARBOXY-RXN
SABIO-RK:
1929
|
|
|
|
3-methylcrotonoyl-CoA + HCO3- + ATP <=> trans-3-methylglutaconyl-CoA + ADP + phosphate + H+
|
6.4.1.4
methylcrotonoyl-CoA carboxylase
6.4.1.5
geranoyl-CoA carboxylase
|
–
–
|
BMK
|
|
BRENDA:
BR156
KEGG:
R04138
MetaCyc:
METHYLCROTONYL-COA-CARBOXYLASE-RXN
SABIO-RK:
3859
|
|
|
|
cis-geranyl-CoA + HCO3- + ATP <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + phosphate + ADP + H+
|
6.4.1.5
geranoyl-CoA carboxylase
|
–
|
MK
|
|
BRENDA:
BR157
KEGG:
R03494
MetaCyc:
GERANOYL-COA-CARBOXYLASE-RXN
|
|
|
|
Cyanate + HCO3- + H+ <=> NH3 + CO2
|
4.2.1.104
cyanase
|
–
|
|
|
BRENDA:
BR22825
KEGG:
R10079
MetaCyc:
RXN-12893
|
|
|
|
phosphate + oxaloacetate <=> phosphoenolpyruvate + HCO3-
|
4.1.1.31
phosphoenolpyruvate carboxylase
|
–
|
M
|
|
BRENDA:
BR290
MetaCyc:
PEPCARBOX-RXN
|
|
|
|
HCO3- <=> H2O + CO2
|
1.6.5.4
monodehydroascorbate reductase (NADH)
4.2.1.1
carbonic anhydrase
|
–
–
|
MK
|
|
BRENDA:
BR3383
KEGG:
R00132;
R10092
MetaCyc:
CARBODEHYDRAT-RXN;
RXN0-5224
SABIO-RK:
703
|
|
|
|
2-Methyl-3-oxopropanoate + CoA + NAD+ + H2O <=> propionyl-CoA + HCO3- + NADH + H+
|
1.2.1.27
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
|
–
|
BM
|
|
BRENDA:
BR36776
MetaCyc:
1.2.1.27-RXN
|
|
|
|
NH3 + HCO3- + ATP <=> Carbamoyl_phosphate + ADP + H2O + H+
|
2.7.2.2
carbamate kinase
|
–
|
BK
|
|
BRENDA:
BR47825
KEGG:
R00150
MetaCyc:
CARBAMATE-KINASE-RXN
|
|
|
|
5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + HCO3- <=> H+ + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate
|
6.3.4.18
5-(carboxyamino)imidazole ribonucleotide synthase
|
–
|
BMK
|
|
BRENDA:
BR48708
KEGG:
R07404
MetaCyc:
RXN0-742
|
|
|
|
Cyanate + HCO3- + H+ <=> Carbamate + CO2
|
4.2.1.104
cyanase
|
–
|
BMK
|
|
BRENDA:
BR48801
KEGG:
R03546
MetaCyc:
R524-RXN
|
|
|
|
acetophenone + HCO3- + ATP + H2O <=> H+ + 3-oxo-3-phenylpropionic_acid + ADP + phosphate
|
6.4.1.8
acetophenone carboxylase
|
–
|
MK
|
|
BRENDA:
BR49511
KEGG:
R05453
MetaCyc:
RXN-1303
|
|
|
|
pyrrole-2-carboxylate + H2O <=> Pyrrole + HCO3-
|
4.1.1.93
pyrrole-2-carboxylate decarboxylase
|
–
|
|
|
BRENDA:
BR49722
KEGG:
R09795
MetaCyc:
RXN-12342
|
|
|
|
2-hydroxyethylphosphonate + O2 <=> methylphosphonate + HCO3- + H+
|
1.13.11.73
methylphosphonate synthase
|
–
|
BMK
|
|
BRENDA:
BR50256
KEGG:
R10191
MetaCyc:
RXN-13856
|
|
|
|
L-threonine + HCO3- + ATP <=> L-threonylcarbamoyladenylate + diphosphate + H2O
|
2.7.7.87
L-threonylcarbamoyladenylate synthase
|
–
|
BM
|
|
BRENDA:
BR50680
KEGG:
R10463
MetaCyc:
RXN-14569
|
|
|
|
S-adenosyl-L-methionine + 3-[(1-carboxyvinyl)oxy]benzoate + H2O <=> 6-amino-6-deoxyfutalosine + L-methionine + HCO3- + H+
|
2.5.1.120
aminodeoxyfutalosine synthase
|
–
|
BMK
|
|
BRENDA:
BR50963
KEGG:
R10667
MetaCyc:
RXN-15264
|
|
|
|
HCO3- + ATP <=> O-Carboxylphosphate + ADP
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
M
|
|
BRENDA:
BR51477
KEGG:
R10948
MetaCyc:
RXN-16909
|
|
|
|
deamido-NAD+ + HCO3- <=> pyridin-1-ium-3,5-dicarboxylate_mononucleotide + AMP + H+
|
2.5.1.143
pyridinium-3,5-biscarboxylic acid mononucleotide synthase
|
–
|
M
|
|
BRENDA:
BR52369
KEGG:
R12017
MetaCyc:
RXN-19042
|
|
|
|
Carbamate + H2O + H+ <=> NH3 + HCO3-
|
2.7.2.2
carbamate kinase
|
–
|
|
|
BRENDA:
BR52486
KEGG:
R12185
MetaCyc:
RXN-19659
|
|
|
|
ATP + acetyl-CoA + HCO3- <=> ADP + phosphate + malonyl-CoA + H+
|
6.4.1.2
acetyl-CoA carboxylase
6.4.1.3
propionyl-CoA carboxylase
6.4.1.4
methylcrotonoyl-CoA carboxylase
|
–
–
–
|
BMK
|
|
BRENDA:
BR6444
KEGG:
R00742
MetaCyc:
ACETYL-COA-CARBOXYLTRANSFER-RXN
SABIO-RK:
542
|
|
|
|
ATP + biotin-carboxyl-carrier_protein + HCO3- <=> ADP + phosphate + carboxybiotin-carboxyl-carrier_protein
|
6.3.4.14
biotin carboxylase
6.4.1.1
pyruvate carboxylase
|
–
–
|
B
|
|
BRENDA:
BR135
KEGG:
R04385
SABIO-RK:
4080
|
|
|
|
ATP + Urea + HCO3- + H+ <=> ADP + phosphate + allophanate
|
6.3.4.6
urea carboxylase
|
–
|
BK
|
|
BRENDA:
BR143
KEGG:
R00774
SABIO-RK:
1126
|
|
|
|
ATP + 2-oxoglutarate + HCO3- <=> ADP + phosphate + oxalosuccinate
|
6.4.1.7
2-oxoglutarate carboxylase
|
–
|
|
|
BRENDA:
BR48777
KEGG:
R08201
|
|
|
|
ATP + butyryl-CoA + HCO3- <=> ADP + ethylmalonyl-CoA + phosphate
|
6.4.1.2
acetyl-CoA carboxylase
6.4.1.3
propionyl-CoA carboxylase
|
–
–
|
|
|
BRENDA:
BS37527
KEGG:
R08924
|
|
|
|
ATP + crotonyl-CoA + HCO3- <=> ADP + phosphate + glutaconyl-CoA
|
6.4.1.4
methylcrotonoyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS369198
SABIO-RK:
13918
|
|
|
|
terephthalate + H2O <=> benzoate + HCO3-
|
not assigned
|
–
|
K
|
|
KEGG:
R07835
|
|
|
|
[biotin_carboxyl-carrier-protein_dimer]-N6-biotinyl-L-lysine + HCO3- + ATP <=> phosphate + [carboxyl-carrier_protein_dimer]-N6-carboxybiotinyl-L-lysine + ADP + H+
|
6.3.4.14
biotin carboxylase
|
–
|
M
|
|
MetaCyc:
BIOTIN-CARBOXYL-RXN
|
|
|
|
(1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + H2O + NAD+ <=> H+ + 3,4-dihydroxybenzoate + NADH + HCO3-
|
1.3.1.53
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
|
–
|
|
|
MetaCyc:
DCDPC-RXN
|
|
|
|
L-2-methyl-3-oxopropionate + CoA + NAD+ + H2O <=> propionyl-CoA + HCO3- + NADH + H+
|
1.2.1.27
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
|
–
|
M
|
|
MetaCyc:
RXN-11213
|
|
|
|
3-oxo-24-ethyl-cholest-4,24-dien-26-oyl-CoA + HCO3- + ATP <=> 3-oxo-24-(isopropanoyl)-cholest-4,24-dien-26-oyl-CoA + ADP + phosphate + H+
|
6.4.1
|
–
|
M
|
|
MetaCyc:
RXN-12782
|
|
|
|
Naphthalene + HCO3- <=> 2-naphthoic_acid + H2O
|
4.1.1
|
–
|
M
|
|
MetaCyc:
RXN-14999
|
|
|
|
HCO3- <=> HCO3- + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18031
|
|
|
|
HCO3- <=> HCO3- + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18032
|
|
|
|
ATP + hexacosanoyl-CoA + HCO3- <=> 2-carboxycerotoyl-CoA + ADP + phosphate + H+
|
6.4.1.3
propionyl-CoA carboxylase
|
–
|
M
|
|
MetaCyc:
RXN1G-4355
|
|
|
|
1-amino-2-ethylcyclopropane-1-carboxylate + ascorbate + O2 + HCO3- <=> 1-Butene + cyanide + dehydroascorbate + CO2 + H2O
|
1.14.17.4
aminocyclopropanecarboxylate oxidase
|
–
|
|
|
BRENDA:
BS375523
|
|
|
|
CNO- + HCO3- + 2 H+ <=> NH3 + 2 CO2
|
4.2.1.104
cyanase
|
–
|
|
|
BRENDA:
BS453472
|
|
|
|
L-2-hydroxy-4-methylthiobutanoic_acid + O2 <=> 3-(methylthio)propanoate + HCO3-
|
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
|
|
|
BRENDA:
BS257500
|
|
|
|
dATP + acetyl-CoA + HCO3- <=> dADP + phosphate + malonyl-CoA
|
6.4.1.2
acetyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS37529
|
|
|
|
GTP + acetyl-CoA + HCO3- <=> GDP + phosphate + malonyl-CoA
|
6.4.1.2
acetyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS369188
|
|
|
|
UTP + acetyl-CoA + HCO3- <=> UDP + phosphate + malonyl-CoA
|
6.4.1.2
acetyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS37530
|
|
|
|
GTP + biotin + HCO3- <=> GDP + phosphate + carboxybiotin
|
6.3.4.14
biotin carboxylase
|
–
|
|
|
BRENDA:
BS679
|
|
|
|
GTP + propionyl-CoA + HCO3- <=> GDP + phosphate + (S)-methylmalonyl-CoA
|
6.4.1.3
propionyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS369193
|
|
|
|
GTP + biotin-carboxyl-carrier_protein + HCO3- <=> GDP + phosphate + carboxybiotin-carboxyl-carrier_protein
|
6.3.4.14
biotin carboxylase
|
–
|
|
|
BRENDA:
BS677
|
|
|
|
formate + NAD+ <=> HCO3- + NADH
|
1.17.1.9
formate dehydrogenase
|
–
|
|
|
BRENDA:
BS439531
|
|
|
|
pyruvate + NAD+ + HCO3- <=> (S)-malate + NADH
|
1.1.1.39
malate dehydrogenase (decarboxylating)
|
–
|
|
|
BRENDA:
BS398232
|
|
|
|
L-carnitine + 2-oxoglutarate + Ozone <=> 3-dehydrocarnitine + succinate + HCO3-
|
1.14.11.1
gamma-butyrobetaine dioxygenase
|
–
|
|
|
BRENDA:
BS451243
|
|
|
|
2-(Acetamidomethylene)succinate + 2 H2O <=> acetate + succinate_semialdehyde + NH3 + HCO3-
|
3.5.1.29
2-(acetamidomethylene)succinate hydrolase
|
–
|
|
|
BRENDA:
BS453340
|
|
|
|
UTP + 3-methylcrotonoyl-CoA + HCO3- <=> UDP + phosphate + trans-3-methylglutaconyl-CoA
|
6.4.1.4
methylcrotonoyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS792
|
|
|
|
UTP + propionyl-CoA + HCO3- <=> UDP + phosphate + (S)-methylmalonyl-CoA
|
6.4.1.3
propionyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS369192
|
|
|
|
Hydroxyurea <=> HCO3- + NH3 + hydroxylamine
|
3.5.1.5
urease
|
–
|
|
|
BRENDA:
BS414717
|
|
|
|
ATP + hydrazine + HCO3- <=> ATP + phosphate + N-amino_carbamoyl_phosphate
|
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
|
|
|
BRENDA:
BS369172
|
|
|
|
ATP + hydroxylamine + HCO3- <=> ATP + phosphate + N-hydroxy_carbamoyl_phosphate
|
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
|
|
|
BRENDA:
BS369171
|
|
|
|
ATP + Urea + HCO3- <=> ADP + phosphate + NH3 + HCO3-
|
6.3.4.6
urea carboxylase
|
–
|
|
|
BRENDA:
BS719
|
|
|
|
ATP + propionyl-CoA + HCO3- + H+ <=> ADP + succinyl-CoA + phosphate
|
6.4.1.2
acetyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS380534
|
|
|
|
ATP + biotin + HCO3- <=> ADP + phosphate + carboxybiotin
|
6.3.4.14
biotin carboxylase
|
–
|
|
|
BRENDA:
BS372448
|
|
|
|
2 ATP + propiophenone + HCO3- + H2O + H+ <=> 2 ADP + 2 phosphate + 3-benzoylpropionate
|
6.4.1.8
acetophenone carboxylase
|
–
|
|
|
BRENDA:
BS411176
|
|
|
|
ATP + butyryl-CoA + HCO3- + H+ <=> ADP + glutaryl-CoA + phosphate
|
6.4.1.2
acetyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS380476
|
|
|
|
ATP + propionyl-CoA + HCO3- <=> ADP + phosphate + methylmalonyl-CoA
|
6.4.1.2
acetyl-CoA carboxylase
6.4.1.3
propionyl-CoA carboxylase
|
–
–
|
|
|
BRENDA:
BS37528
|
|
|
|
2 ATP + 4-acetylpyridine + HCO3- + H2O + H+ <=> 2 ADP + 2 phosphate + 2-oxo-3-(pyridin-4-yl)propanoate
|
6.4.1.8
acetophenone carboxylase
|
–
|
|
|
BRENDA:
BS411171
|
|
|
|
selenate + Lactate <=> Selenite + H2O + acetate + HCO3-
|
1.97.1.9
selenate reductase
|
–
|
|
|
BRENDA:
BS359487
|
|
|
|
2 ATP + HCO3- + NH3 + L-ornithine <=> 2 ADP + 2 phosphate + H2O + L-citrulline
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
|
–
|
|
|
SABIO-RK:
9636
|
|
|
|
ATP + HCO3- + H2O <=> phosphate + CO2 + ADP
|
6.3.4.14
biotin carboxylase
|
–
|
|
|
SABIO-RK:
8073
|
|